Structure of PDB 3wlx Chain B

Receptor sequence
>3wlxB (length=332) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKE
AAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQP
QPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLK
EAWEFTRERNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLG
TPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGIYALKNNVARLQ
EDHDNAAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVL
INASPIVRLVTHLDVSREQLAEVAAHWRAFLA
3D structure
PDB3wlx Structure analysis of L-threonine aldolase from Escherichia coli unravels the low-specificity and thermostability
ChainB
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.2.48: low-specificity L-threonine aldolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLG B S6 G58 T59 H83 E136 D166 A168 R169 K197 R308 S6 G58 T59 H83 E136 D166 A168 R169 K197 R308
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008732 L-allo-threonine aldolase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
GO:0050179 phenylserine aldolase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006545 glycine biosynthetic process
GO:0006567 threonine catabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3wlx, PDBe:3wlx, PDBj:3wlx
PDBsum3wlx
PubMed
UniProtP75823|LTAE_ECOLI Low specificity L-threonine aldolase (Gene Name=ltaE)

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