Structure of PDB 3w00 Chain B

Receptor sequence
>3w00B (length=226) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
YDVTEWKHVFKLDPNKDLPDEQLEILCESGTDAVIIGGSDGVTEDNVLRM
MSKVRRFLVPCVLEVSAIEAIVPGFDLYFIPSVLNSKNADWIVGMHQKAM
KEYGELMSMEEIVAEGYCIANPDCKAAALTEADADLNMDDIVAYARVSEL
LQLPIFYLEYSGVLGDIEAVKKTKAVLETSTLFYGGGIKDAETAKQYAEH
ADVIVVGNAVYEDFDRALKTVAAVKG
3D structure
PDB3w00 Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.n9: heptaprenylglyceryl phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FPS B S40 V66 W92 H97 K126 S39 V65 W91 H96 K125
BS02 1GP B K12 Y158 E160 S162 G208 N209 K11 Y157 E159 S161 G207 N208
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0002094 polyprenyltransferase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0046872 metal ion binding
Biological Process
GO:0006650 glycerophospholipid metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0046474 glycerophospholipid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3w00, PDBe:3w00, PDBj:3w00
PDBsum3w00
PubMed23322418
UniProtO34790|PCRB_BACSU Heptaprenylglyceryl phosphate synthase (Gene Name=pcrB)

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