Structure of PDB 3vq7 Chain B

Receptor sequence
>3vq7B (length=141) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
SSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTVHTDNGSNFTSTTVKAACDWAGIKQEDSMNKELKKIIGQVRDQ
AEHLKTAVQMAVFIHNHKRKGGIGGYSAGERIVDIIATDIQ
3D structure
PDB3vq7 Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
ChainB
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLC B V88 K173 V33 K105
BS02 FRU B E96 Y99 K103 E41 Y44 K48
BS03 SNU B N184 H185 G197 E198 N116 H117 G129 E130
BS04 SNU B T174 M178 T106 M110
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3vq7, PDBe:3vq7, PDBj:3vq7
PDBsum3vq7
PubMed23139382
UniProtQ72498

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