Structure of PDB 3vps Chain B

Receptor sequence

>3vpsB (length=301) Species: 1079985 (Streptomyces chartreusis NRRL 3882) [Search protein sequence]

HRILITGGAGFIGGHLARALVASGEEVTVLDDLRVPPMIPPEGTGKFLEK
PVLELEERDLSDVRLVYHLASHKSVPRSFKQPLDYLDNVDSGRHLLALCT
SVGVPKVVVGSTCEVYGQADTLPTPEDSPLSPRSPYAASKVGLEMVAGAH
QRASVAPEVGIVRFFNVYGPGERPDALVPRLCANLLTRNELPVEGDGEQR
RDFTYITDVVDKLVALANRPLPSVVNFGSGQSLSVNDVIRILQATSPAAE
VARKQPRPNEITEFRADTALQTRQIGEGGIGIEEGIRLTLEWWQSRDLDD
I

3D structure

PDB

3vps Biosynthesis of nucleoside antibiotic tunicamycin proceeds via unique exo-glycal intermediates

Chain

Resolution

1.9 Å

3D
structure

Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Catalytic site (original residue number in PDB)	T119 C120 E121 Y143 K147 D182
Catalytic site (residue number reindexed from 1)	T112 C113 E114 Y136 K140 D175
Enzyme Commision number	4.2.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	UD1	B	K80 T119 C120 E121 Y143 N173 D182 A183 L184 R187 P199 E201 Q206 R208 V242 R264 E267	K73 T112 C113 E114 Y136 N166 D175 A176 L177 R180 P192 E194 Q199 R201 V235 R257 E260
BS02	NAD	B	G14 G17 F18 I19 D38 D39 R41 V42 P58 V59 L76 A77 S78 K80 K147 F171 V174	G7 G10 F11 I12 D31 D32 R34 V35 P51 V52 L69 A70 S71 K73 K140 F164 V167

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding

View graph for
Molecular Function

External links

PDB	RCSB:3vps, PDBe:3vps, PDBj:3vps
PDBsum	3vps
PubMed
UniProt	E5KJ94

[Back to BioLiP]