Structure of PDB 3vom Chain B

Receptor sequence
>3vomB (length=368) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
LEIPTAIKPRDGRFGSGPSKVRLEQLQTLTTTAAALFGTSHRQAPVKNLV
GRVRSGLAELFSLPDGYEVILGNGGATAFWDAAAFGLIDKRSLHLTYGEF
SAKFASAVSKNPFVGEPIIITSDPGSAPEPQTDPSVDVIAWAHNETSTGV
AVAVRRPEGSDDALVVIDATSGAGGLPVDIAETDAYYFAPQKNFASDGGL
WLAIMSPAALSRIEAIAATGRWVPDFLSLPIAVENSLKNQTYNTPAIATL
ALLAEQIDWLVGNGGLDWAVKRTADSSQRLYSWAQERPYTTPFVTDPGLR
SQVVGTIDFVDDVDAGTVAKILRANGIVDTEPYRKLGRNQLRVAMFPAVE
PDDVSALTECVDWVVERL
3D structure
PDB3vom Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
ChainB
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F108 D176 K200
Catalytic site (residue number reindexed from 1) F100 D168 K192
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B N251 T252 N243 T244
BS02 PLP B A84 T85 W88 F108 T154 D176 T178 Q199 K200 A76 T77 W80 F100 T146 D168 T170 Q191 K192
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0004760 L-serine-pyruvate transaminase activity
GO:0008453 alanine-glyoxylate transaminase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
GO:0008615 pyridoxine biosynthetic process
GO:0009058 biosynthetic process
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3vom, PDBe:3vom, PDBj:3vom
PDBsum3vom
PubMed22525753
UniProtP9WQ73|SERC_MYCTU Phosphoserine aminotransferase (Gene Name=serC)

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