Structure of PDB 3ve7 Chain B

Receptor sequence
>3ve7B (length=205) Species: 399549 (Metallosphaera sedula DSM 5348) [Search protein sequence]
MNRVILSLDSPIPEETLRKLNGKVAGIKVGWPLLLNLGKEKVKELVGLVD
GIKILDLKLADIDNTMILIVDELKDITNSFIAHAFVGVEGSLASLSQRVD
LFLVLSMSHPGWNDAFYPYLREVARRVNPKGFVAPATRPSMISRVKGDFP
DKLVISPGVGTQGAKPGIALCHGADYEIVGRSVYQSADPVRKLEEIVRSQ
EEVLS
3D structure
PDB3ve7 Crystal structure of orotidine 5'-monophosphate decarboxylase from Metallosphaera sedula complexed with inhibitor BMP
ChainB
Resolution1.539 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.23: orotidine-5'-phosphate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMP B D61 I62 T65 D61 I62 T65
BS02 BMP B S7 D9 K58 M107 S108 P157 Q162 G180 R181 S7 D9 K58 M107 S108 P157 Q162 G180 R181
Gene Ontology
Molecular Function
GO:0004590 orotidine-5'-phosphate decarboxylase activity
GO:0016831 carboxy-lyase activity
Biological Process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0044205 'de novo' UMP biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3ve7, PDBe:3ve7, PDBj:3ve7
PDBsum3ve7
PubMed
UniProtA4YI54

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