Structure of PDB 3vc1 Chain B

Receptor sequence
>3vc1B (length=278) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence]
PAPATPYQEDIARYWNNEARPVNLRLGDVDGLYHHHYGIGPVDRAALGDP
EHSEYEKKVIAELHRLESAQAEFLMDHLGQAGPDDTLVDAGCGRGGSMVM
AHRRFGSRVEGVTLSAAQADFGNRRARELRIDDHVRSRVCNMLDTPFDKG
AVTASWNNESTMYVDLHDLFSEHSRFLKVGGRYVTITGCWNPRYGQPSKW
VSQINAHFECNIHSRREYLRAMADNRLVPHTIVDLTPDTLPYWELRATSS
LVTGIEKAFIESYRDGSFQYVLIAADRV
3D structure
PDB3vc1 Structure of Geranyl Diphosphate C-Methyltransferase from Streptomyces coelicolor and Implications for the Mechanism of Isoprenoid Modification.
ChainB
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.255: geranyl diphosphate 2-C-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B Q22 W29 H49 H50 G105 C106 G107 T127 L128 Q132 C154 N155 M156 N172 Y177 Q8 W15 H35 H36 G91 C92 G93 T113 L114 Q118 C140 N141 M142 N158 Y163
BS02 GST B W29 R34 V36 N37 H49 Y51 M176 F222 R260 W15 R20 V22 N23 H35 Y37 M162 F208 R246
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008168 methyltransferase activity
GO:0008169 C-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:1904047 S-adenosyl-L-methionine binding
Biological Process
GO:0032259 methylation
GO:0042214 terpene metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3vc1, PDBe:3vc1, PDBj:3vc1
PDBsum3vc1
PubMed22455498
UniProtQ9F1Y5|GPPMT_STRCO Geranyl diphosphate 2-C-methyltransferase (Gene Name=SCO7701)

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