Structure of PDB 3uwv Chain B

Receptor sequence
>3uwvB (length=254) Species: 282458 (Staphylococcus aureus subsp. aureus MRSA252) [Search protein sequence]
SMRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDAL
TTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSE
RRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQV
KKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADL
SSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLL
EGAK
3D structure
PDB3uwv Crystal structures of triosephosphate isomerase from methicillin resistant Staphylococcus aureus MRSA252 provide structural insights into novel modes of ligand binding and unique conformations of catalytic loop
ChainB
Resolution2.07 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N9 K11 H97 E99 E169 G175 S215
Catalytic site (residue number reindexed from 1) N10 K12 H98 E100 E170 G176 S216
Enzyme Commision number 5.3.1.1: triose-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2PG B K11 G236 G237 K12 G237 G238
Gene Ontology
Molecular Function
GO:0004807 triose-phosphate isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0019563 glycerol catabolic process
GO:0046166 glyceraldehyde-3-phosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3uwv, PDBe:3uwv, PDBj:3uwv
PDBsum3uwv
PubMed22813930
UniProtQ6GIL6|TPIS_STAAR Triosephosphate isomerase (Gene Name=tpiA)

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