Structure of PDB 3uuc Chain B

Receptor sequence
>3uucB (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
LEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMVVPLYDLLLEMLDAHRLHAP
3D structure
PDB3uuc Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 0D1 B T347 A350 E353 L387 M421 L525 T42 A45 E48 L82 M113 L207
External links
PDB RCSB:3uuc, PDBe:3uuc, PDBj:3uuc
PDBsum3uuc
PubMed22927406
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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