Structure of PDB 3utg Chain B

Receptor sequence

>3utgB (length=505) Species: 746128 (Aspergillus fumigatus)

HPDISVDVLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGGLASTDVT
PEGFLYDVGGHVIFSHYKYFDDCLDEALPKEDDWYTHQRISYVRCQGQWV
PYPFQNNISMLPKEEQVKCIDGMIDAALEARVANTKPKTFDEWIVRMMGT
GIADLFMRPYNFKVWAVPTTKMQCAWLGERVAAPNLKAVTTNVILGKTAG
NWGPNATFRFPARGGTGGIWIAVANTLPKEKTRFGEKGKVTKVNANNKTV
TLQDGTTIGYKKLVSTMAVDFLAEAMNDQELVGLTKQLFYSSTHVIGVGV
RGSRPERIGDKCWLYFPEDNCPFYRATIFSNYSPYNQPEASAALPTMQLA
DGSRPQSTEAKEGPYWSIMLEVSESSMKPVNQETILADCIQGLVNTEMLK
PTDEIVSTYHRRFDHGYPTPTLEREGTLTQILPKLQDKDIWSRGRFGSWR
YEVGNQDHSFMLGVEAVDNIVNGAVELTLNYPDFVNGRQNTERRLVDGAQ
VFAKS

3D structure

• PDB: 3utg Crystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic Fungus Aspergillus fumigatus.
• Chain: B
• Resolution: 2.25 Å

Enzymatic activity

• Enzyme Commision number: 5.4.99.9: UDP-galactopyranose mutase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FDA	B	G14 G16 P17 T18 D38 S39 G45 L46 V60 G62 H63 V64 V242 M269 G446 R447 G456 N457 Q458 S461	G12 G14 P15 T16 D36 S37 G43 L44 V58 G60 H61 V62 V240 M267 G444 R445 G454 N455 Q456 S459
BS02	UDP	B	Y104 P105 F106 Q107 F158 N163 Y317 R327 Y419 Y453	Y102 P103 F104 Q105 F156 N161 Y315 R325 Y417 Y451

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0008767 UDP-galactopyranose mutase activity
• GO:0016853 isomerase activity

Biological Process

• GO:0071555 cell wall organization

External links

• PDB: RCSB:3utg, PDBe:3utg, PDBj:3utg
• PDBsum: 3utg
• PubMed: 22294687
• UniProt: Q4W1X2|GLFA_ASPFM UDP-galactopyranose mutase (Gene Name=glfA)