Structure of PDB 3uk6 Chain B

Receptor sequence
>3uk6B (length=300) Species: 9606 (Homo sapiens) [Search protein sequence]
GAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRA
VLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQA
FRRSIGVRIVHTVSLHEIDVINSRFLALFSGDTGEIKSEVREQINAKVAE
WIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTS
YQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTV
LTRIGLETSLRYAIQLITAASLVCREVQVDDIKRVYSLFLDESRSTQYMK
3D structure
PDB3uk6 Large-Scale Conformational Flexibility Determines the Properties of AAA+ TIP49 ATPases.
ChainB
Resolution2.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B A24 H25 H27 M46 V47 G80 T81 G82 K83 T84 A85 Y362 I370 A2 H3 H5 M24 V25 G58 T59 G60 K61 T62 A63 Y223 I231
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:3uk6, PDBe:3uk6, PDBj:3uk6
PDBsum3uk6
PubMed22748767
UniProtQ9Y230|RUVB2_HUMAN RuvB-like 2 (Gene Name=RUVBL2)

[Back to BioLiP]