Structure of PDB 3uiw Chain B

Receptor sequence
>3uiwB (length=109) Species: 7955 (Danio rerio) [Search protein sequence]
GLSSSACGQFVQDIVSSNCVVIFSKTTCPYCKMAKGVFNEIGATYKVVEL
DEHNDGRRLQETLAELTGARTVPRVFINGQCIGGGSDTKQLHQQGKLLPL
IEQCRPCCL
3D structure
PDB3uiw A New Mode of Iron-sulfur Cluster Coordination in Glutaredoxins is Crucial for Axonogenesis
ChainB
Resolution2.601 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH B K34 C37 Y39 T80 V81 G94 S95 K25 C28 Y30 T71 V72 G85 S86
Gene Ontology
Molecular Function
GO:0015038 glutathione disulfide oxidoreductase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0001755 neural crest cell migration
GO:0001944 vasculature development
GO:0003147 neural crest cell migration involved in heart formation
GO:0007417 central nervous system development
GO:0008347 glial cell migration
GO:0034599 cellular response to oxidative stress
GO:0060914 heart formation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3uiw, PDBe:3uiw, PDBj:3uiw
PDBsum3uiw
PubMed
UniProtQ6DH06

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