Structure of PDB 3uf5 Chain B

Receptor sequence
>3uf5B (length=144) Species: 10090 (Mus musculus) [Search protein sequence]
KEVSEHCSHMIGNGHLKVLQQLIDSQMETSCQIAFEFVDQEQLDDPVCYL
KKAFFLVQDIIDETMRFKDNTPNANATERLQELSNNLNSCFTKDYENKAC
VRTFHETPLQLLEKIKNFFNETKNLLEKDWNIFTKNCNNSFAKC
3D structure
PDB3uf5 Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA B N138 C139 N140 N141 N136 C137 N138 N139
Gene Ontology
Molecular Function
GO:0005125 cytokine activity
GO:0008083 growth factor activity
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:3uf5, PDBe:3uf5, PDBj:3uf5
PDBsum3uf5
PubMed22902366
UniProtP07141|CSF1_MOUSE Macrophage colony-stimulating factor 1 (Gene Name=Csf1)

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