Structure of PDB 3uds Chain B

Receptor sequence
>3udsB (length=352) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
WIYRGEGGANLVLAYAGSSPLFVGKVIRIQKVLTSDEQHLWRENNELISS
PNKEVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPL
WRVNAANVDTSHDSALILNDHSLFSCISVEIKPKCGFLPTSRFIGKENIL
KTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTP
QNNFRVFLNGSLILGGTGRTSPEIGYAFEDALKGFIGHRTECFLQLVSDA
VYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPALPLDESLKIVKEYL
IAATAKDCSIMISFQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNR
KQ
3D structure
PDB3uds Inositol phosphate-induced stabilization of inositol 1,3,4,5,6-pentakisphosphate 2-kinase and its role in substrate specificity.
ChainB
Resolution3.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.1.158: inositol-pentakisphosphate 2-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B E18 G19 G20 A21 N22 V24 V38 R40 N147 D148 H149 E166 M372 D407 E6 G7 G8 A9 N10 V12 V26 R28 N119 D120 H121 E130 M311 D325
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0032942 inositol-1,4,5,6-tetrakisphosphate 2-kinase activity
GO:0035299 inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity
GO:0046872 metal ion binding
GO:0102731 inositol-1,3,4,6-tetrakisphosphate 2-kinase activity
Biological Process
GO:0010264 myo-inositol hexakisphosphate biosynthetic process
GO:0016310 phosphorylation
GO:0030643 intracellular phosphate ion homeostasis
GO:0042742 defense response to bacterium
GO:0048527 lateral root development
GO:0050832 defense response to fungus
GO:0051607 defense response to virus
GO:0055062 phosphate ion homeostasis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3uds, PDBe:3uds, PDBj:3uds
PDBsum3uds
PubMed22362712
UniProtQ93YN9|IPPK_ARATH Inositol-pentakisphosphate 2-kinase (Gene Name=IPK1)

[Back to BioLiP]