Structure of PDB 3u2v Chain B

Receptor sequence

>3u2vB (length=263) Species: 9606 (Homo sapiens)

SMTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRLVVLATPQVSDSMRK
VLETVFDEVIMVDVLDSGDSAHLTLMKRPELGVTLTKLHCWSLTQYSKCV
FMDADTLVLANIDDLFDREELSAAPDPGWPDCFNSGVFVYQPSVETYNQL
LHLASEQGSFDGGDQGILNTFFSSWATTDIRKHLPFIYNLSSISIYSYLP
AFKVFGASAKVVHFLGRVKPWNYTYDPKTKSVKSEAHDPNMTHPEFLILW
WNIFTTNVLPLLQ

3D structure

• PDB: 3u2v Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis.
• Chain: B
• Resolution: 1.5 Å

Enzymatic activity

• Enzyme Commision number: 2.4.1.186: glycogenin glucosyltransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	B	R216 H236	R217 H237
BS02	GLC	B	G215 R216 P238	G216 R217 P239
BS03	GLC	B	M75 D125 Q164	M76 D126 Q165
BS04	GLC	B	D102 N133 S134 D160 G162 D163 Q164	D103 N134 S135 D161 G163 D164 Q165
BS05	MN	B	D102 D104 H212	D103 D105 H213
BS06	UDP	B	L9 T10 T11 Y15 R77 L80 T83 D102 A103 D104 H212 L214 K218	L10 T11 T12 Y16 R78 L81 T84 D103 A104 D105 H213 L215 K219

Gene Ontology

Molecular Function

• GO:0016757 glycosyltransferase activity

External links

• PDB: RCSB:3u2v, PDBe:3u2v, PDBj:3u2v
• PDBsum: 3u2v
• PubMed: 22160680
• UniProt: P46976|GLYG_HUMAN Glycogenin-1 (Gene Name=GYG1)