Structure of PDB 3u2d Chain B

Receptor sequence
>3u2dB (length=186) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
QVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEV
VIEKDNWIKVTDNGRGIPVDIQEGRPAVEVILTSSVVNALSQDLEVYVHR
NETIYHQAYKKGVPQFDLKEVGTTDKTGTVIRFKADGEIFTETTVYNYET
LQQRIRELAFLNKGIQITLRDERDEENVREDSYHYE
3D structure
PDB3u2d Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 08B B N54 E58 D81 R84 G85 I86 P87 I175 N35 E39 D62 R65 G66 I67 P68 I131
BS02 MG B G208 H228 G164 H184
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:3u2d, PDBe:3u2d, PDBj:3u2d
PDBsum3u2d
PubMed22183167
UniProtP0A0K8|GYRB_STAAU DNA gyrase subunit B (Gene Name=gyrB)

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