Structure of PDB 3u1n Chain B

Receptor sequence
>3u1nB (length=434) Species: 9606 (Homo sapiens) [Search protein sequence]
PGDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEH
SLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMF
DGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICF
IKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLG
IQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAY
QHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTD
NIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYE
SLPKEVASAKPKVLLDVKLKAEDFIVDVINMHVSFYCKTAPNRAIRAEQL
IRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQD
3D structure
PDB3u1n HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 B R164 D207 H215 D311 R47 D90 H98 D187
BS02 ZN B H167 H206 D207 D311 H50 H89 D90 D187
External links
PDB RCSB:3u1n, PDBe:3u1n, PDBj:3u1n
PDBsum3u1n
PubMed22056990
UniProtQ9Y3Z3|SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (Gene Name=SAMHD1)

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