Structure of PDB 3tzz Chain B

Receptor sequence
>3tzzB (length=465) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
PGVTEEALRLKEAALEELAAQEVTAPLVPLAVSAFLTSRKKAAAAELADW
MQSPEGQASSLESIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAAGKQ
APNVFSVDGPVTTGPVWVLAGFGAQHRKMGKSLYLRNEVFAAWIEKVDAL
VQDELGYSVLELILDDAQDYGIETTQVTIFAIQIALGELLRHHGAKPAAV
IGQSLGEAASAYFAGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMAL
VEYSADEIREVFSDFPDLEVCVYAAPTQTVIGGPPEQVDAILARAEAEGK
FARKFATKGASHTSQMDPLLGELTAELQGIKPTSPTCGIFSTVHEGRYIK
PGGEPIHDVEYWKKGLRHSVYFTHGIRNAVDSGHTTFLELAPNPVALMQV
ALTTADAGLHDAQLIPTLARKQDEVSSMVSTMAQLYVYGHDLDIRTLFSR
ASGPQDYANIPPTRF
3D structure
PDB3tzz Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13
ChainB
Resolution2.49 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S801 L802 R826 H909 G962
Catalytic site (residue number reindexed from 1) S204 L205 R229 H312 G365
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B L624 L678 H680 P699 N700 F702 P1013 Q1019 S1027 L27 L81 H83 P102 N103 F105 P416 Q422 S430
BS02 XPM B F719 Q773 S801 L802 R826 M830 G833 E834 L837 T904 S908 H909 M913 F122 Q176 S204 L205 R229 M233 G236 E237 L240 T307 S311 H312 M316
Gene Ontology
Molecular Function
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:3tzz, PDBe:3tzz, PDBj:3tzz
PDBsum3tzz
PubMed22825853
UniProtO53579

[Back to BioLiP]