Structure of PDB 3tsb Chain B

Receptor sequence
>3tsbB (length=434) Species: 198094 (Bacillus anthracis str. Ames) [Search protein sequence]
ENLYFQSNAMWESKFVKEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQ
LNIPLISAGMDTVTEADMAIAMARQGGLGIIHKNMSIEQQAEQVDKVKRS
ESGVGVPIITNRDMRFILITAPVGTTLSEAEKILQKYKIEKLPLVLITIK
DIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDALVKASVDAIVLDT
AHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVKVGI
GPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVK
ALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKGSK
DRYFQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLE
FLRENAQFIRMSGAGLLESHPHHVQITKEAPNYS
3D structure
PDB3tsb Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
ChainB
Resolution2.595 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 B G305 S306 S365 Y388 G253 S254 S313 Y336
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006177 GMP biosynthetic process
GO:0006183 GTP biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3tsb, PDBe:3tsb, PDBj:3tsb
PDBsum3tsb
PubMed22788966
UniProtA0A6L8P2U9

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