Structure of PDB 3tg6 Chain B

Receptor sequence
>3tg6B (length=423) Species: 381518 (Influenza A virus (A/Wilson-Smith/1933(H1N1))) [Search protein sequence]
ATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAF
DERRNKYLEEHPKDPKKTGGPIYRRVDGKWRRELILYDKEEIRRIWRQAN
NGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPR
RSGAAGAAVKGVGTMVMELIRMIKRRTRIAYERMCNILKGKFQTAAQRTM
VDQVRESRNPGNAEFEDLIFLARSALILRGSVAHKSCLPACVYGSAVASG
YDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAF
EDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAI
RTRSGGQISIQPTFSVQRNLPFDRPTIMAARTEIIRLMESARPEDVSFQG
RGVFELSDEKATSPIVPSYFFGD
3D structure
PDB3tg6 Biophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 0MM B Y52 E53 R99 W104 Y313 S376 Y31 E32 R75 W80 Y275 S338
BS02 0MM B Y289 Y296 D302 R305 L306 N309 Y251 Y258 D264 R267 L268 N271
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075732 viral penetration into host nucleus
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3tg6, PDBe:3tg6, PDBj:3tg6
PDBsum3tg6
PubMed
UniProtQ1K9H2

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