Structure of PDB 3tdj Chain B

Receptor sequence
>3tdjB (length=260) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKY
KLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVID
FSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSK
IAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIE
QRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLK
NKWWYDKGEC
3D structure
PDB3tdj Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2.
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3TJ B P105 S108 S217 K218 G219 P104 S107 S216 K217 G218 PDBbind-CN: -logKd/Ki=5.25,Kd=5.6uM
BS02 3TJ B P105 F106 M107 S108 P104 F105 M106 S107 PDBbind-CN: -logKd/Ki=5.25,Kd=5.6uM
BS03 GLU B Y61 T91 R96 G141 S142 T143 E193 Y60 T90 R95 G140 S141 T142 E192
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3tdj, PDBe:3tdj, PDBj:3tdj
PDBsum3tdj
PubMed21895609
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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