Structure of PDB 3t6a Chain B

Receptor sequence
>3t6aB (length=308) Species: 9606 (Homo sapiens) [Search protein sequence]
TVSSFRPNEFESKFLPPENKPLETALLKRAKELFTNNDPKVIAQHVLSMD
CRVARILGVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERHNTMAIGIA
VDILGCTGTLEDRAATLSKIIQVAVELKDSMGDLYSFSALMKALEMPQIT
RLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRESTCVPPNNVSVPLL
MPLVTLMERQAVTFEGTDMWEKNDQSCEIMLNHLATARFMAEAADSYRMN
AERILAGFQPDEEMNEICKTEFQMRLLWGSKGAQVNQTERYEKFNQILTA
LSRKLEPP
3D structure
PDB3t6a NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 POG B A745 T746 A235 T236
Gene Ontology
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:3t6a, PDBe:3t6a, PDBj:3t6a
PDBsum3t6a
PubMed22081014
UniProtO75815|BCAR3_HUMAN Breast cancer anti-estrogen resistance protein 3 (Gene Name=BCAR3)

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