Structure of PDB 3t4e Chain B

Receptor sequence
>3t4eB (length=283) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
TAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAI
EGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRG
YNTDGTGHIRAIKESGFDMRGKTMVLLGAGGAATAIGAQAAIEGIKEIKL
FNRKDDFFEKAVAFAKRVNENTDCVVTVTDLADQHAFTEALASADILTNG
TKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTKLLQQAQQAGCKTI
DGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGF
3D structure
PDB3t4e 1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD.
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.282: quinate/shikimate dehydrogenase [NAD(P)(+)].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G131 G133 G134 A135 N155 R156 D158 F160 T204 K205 V206 M208 C232 Y234 M258 L259 G128 G130 G131 A132 N152 R153 D155 F157 T201 K202 V203 M205 C229 Y231 M255 L256
Gene Ontology
Molecular Function
GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
GO:0030266 quinate 3-dehydrogenase (NAD+) activity
GO:0052733 quinate 3-dehydrogenase (NADP+) activity
GO:0052734 shikimate 3-dehydrogenase (NAD+) activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
GO:0019632 shikimate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3t4e, PDBe:3t4e, PDBj:3t4e
PDBsum3t4e
PubMed
UniProtQ8ZPR4|YDIB_SALTY Quinate/shikimate dehydrogenase (Gene Name=ydiB)

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