Structure of PDB 3si5 Chain B

Receptor sequence
>3si5B (length=149) Species: 9606 (Homo sapiens) [Search protein sequence]
GSQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLER
AVEALQGEKRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQF
YISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSRQ
3D structure
PDB3si5 Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B E103 V106 W125 L131 C132 D137 M138 Y141 E49 V52 W71 L77 C78 D83 M84 Y87
Gene Ontology
Biological Process
GO:0007094 mitotic spindle assembly checkpoint signaling

View graph for
Biological Process
External links
PDB RCSB:3si5, PDBe:3si5, PDBj:3si5
PDBsum3si5
PubMed22000412
UniProtO60566|BUB1B_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (Gene Name=BUB1B)

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