Structure of PDB 3shv Chain B

Receptor sequence
>3shvB (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
KPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRT
LNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSHHFPAAPLCRSEC
HLSAGPYRGTLFADQPAMFVSPASSPPVAKLCELVHLCGGRVSQVPRQAS
IVIGPYSGKKKATVKYLSEKWVLDSITQHKVCAPENYLLS
3D structure
PDB3shv Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B T653 S654 L692 R693 T694 N696 P770 T9 S10 L48 R49 T50 N52 P126
External links
PDB RCSB:3shv, PDBe:3shv, PDBj:3shv
PDBsum3shv
PubMed22154951
UniProtQ8NEM0|MCPH1_HUMAN Microcephalin (Gene Name=MCPH1)

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