Structure of PDB 3s86 Chain B

Receptor sequence
>3s86B (length=189) Species: 2336 (Thermotoga maritima) [Search protein sequence]
KLTVYLATTNPHKVEEIKMIAPEWMEILPSPEKIEVVEDGETFLENSVKK
AVVYGKKLKHPVMADDSGLVIYSLGGFPGVMSARFMEEHSYKEKMRTILK
MLEGKDRRAAFVCSATFFDPVENTLISVEDRVEGRIANEIRGTGGFGYDP
FFIPDGYDKTFGEIPHLKEKISHRSKAFRKLFSVLEKIL
3D structure
PDB3s86 Structural and functional characterization of a noncanonical nucleoside triphosphate pyrophosphatase from Thermotoga maritima.
ChainB
Resolution2.15 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.66: XTP/dITP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP B K15 E40 D68 S69 S84 A85 Y93 F113 F148 Y150 D151 K170 H175 R176 K13 E38 D66 S67 S82 A83 Y91 F111 F146 Y148 D149 K168 H173 R174
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0035870 dITP diphosphatase activity
GO:0036220 ITP diphosphatase activity
GO:0036222 XTP diphosphatase activity
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity
Biological Process
GO:0009117 nucleotide metabolic process
GO:0009143 nucleoside triphosphate catabolic process
GO:0009146 purine nucleoside triphosphate catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3s86, PDBe:3s86, PDBj:3s86
PDBsum3s86
PubMed23385455
UniProtQ9WY06|IXTPA_THEMA dITP/XTP pyrophosphatase (Gene Name=TM_0159)

[Back to BioLiP]