Structure of PDB 3s4s Chain B

Receptor sequence
>3s4sB (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]
MGDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRA
VTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKV
TVYPSQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT
FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB3s4s Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F13 P56 D57 W61 L67 Q70 R71 Y78 H81 N82 V85 F14 P57 D58 W62 L68 Q71 R72 Y79 H82 N83 V86
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3s4s, PDBe:3s4s, PDBj:3s4s
PDBsum3s4s
PubMed21900604
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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