Structure of PDB 3rw6 Chain B

Receptor sequence
>3rw6B (length=244) Species: 9606 (Homo sapiens) [Search protein sequence]
KNWFKITIPYGRKYDKAWLLSMIQSKCSVPFTPIEFHYENTRAQFFVEDA
STASALKAVNYKILDRENRRISIIINSSAPPHTILNELKPEQVEQLKLIM
SKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPE
LLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKGLK
LEELWLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELPPPI
3D structure
PDB3rw6 Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
ChainB
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B T123 P125 Y126 E151 H153 Y154 N156 R158 Y177 N192 H198 R233 V246 N248 N275 R276 Y278 R279 K304 S305 T7 P9 Y10 E35 H37 Y38 N40 R42 Y61 N76 H82 R117 V130 N132 N159 R160 Y162 R163 K188 S189 PDBbind-CN: Kd=0.09uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006406 mRNA export from nucleus
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3rw6, PDBe:3rw6, PDBj:3rw6
PDBsum3rw6
PubMed21822283
UniProtQ9UBU9|NXF1_HUMAN Nuclear RNA export factor 1 (Gene Name=NXF1)

[Back to BioLiP]