Structure of PDB 3ro5 Chain B

Receptor sequence
>3ro5B (length=423) Species: 381518 (Influenza A virus (A/Wilson-Smith/1933(H1N1))) [Search protein sequence]
ATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAF
DERRNKYLEEHPDPKKTGGPIYRRVDGKWRRELILYDKEEIRRIWRQANN
GDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRR
SGAAGAAVKGVGTMVMELIRMIKRRTRIAYERMCNILKGKFQTAAQRTMV
DQVRESRPGNAEFEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYD
FEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFED
LRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRT
RSGGQISIQPTFSVQRNLPFDRPTIMAARTEIIRLMESARPEDVSFQGRG
VFELSDEKATSPIVPSFSYFFGD
3D structure
PDB3ro5 Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.
ChainB
Resolution2.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LGH B Y52 R99 W104 Y313 S376 Y31 R74 W79 Y273 S336
BS02 LGH B Y289 Y296 D302 R305 L306 N309 Y249 Y256 D262 R265 L266 N269
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075732 viral penetration into host nucleus
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ro5, PDBe:3ro5, PDBj:3ro5
PDBsum3ro5
PubMed21896751
UniProtQ1K9H2

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