Structure of PDB 3rkq Chain B

Receptor sequence
>3rkqB (length=57) Species: 9606 (Homo sapiens) [Search protein sequence]
GRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWF
QNRRYKS
3D structure
PDB3rkq Crystal structure of the human NKX2.5 homeodomain in complex with DNA target.
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B Y162 R168 K183 Q187 R190 Y191 Y26 R32 K47 Q51 R54 Y55
BS02 dna B R142 L144 F145 Q181 N188 R6 L8 F9 Q45 N52
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3rkq, PDBe:3rkq, PDBj:3rkq
PDBsum3rkq
PubMed22849347
UniProtP52952|NKX25_HUMAN Homeobox protein Nkx-2.5 (Gene Name=NKX2-5)

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