Structure of PDB 3rf5 Chain B

Receptor sequence
>3rf5B (length=116) Species: 53326 (Ancylostoma ceylanicum) [Search protein sequence]
PMVRVATNLPDKDVPANFEERLTDLLAESMNKPRNRIAIEVLAGQRITHG
ASRNPVAVIKVESIGALSADDNIRHTQKITQFCQDTLKLPKDKVIITYFD
LQPIHVGFNGTTVAAA
3D structure
PDB3rf5 Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUZ B P1 M2 K32 R36 I64 F108 V113 P1 M2 K32 R36 I64 F108 V113 MOAD: Ki=2.37uM
BS02 ZN B E20 D24 E20 D24
BS03 FUZ B H49 I95 H49 I95 MOAD: Ki=2.37uM
Gene Ontology
Molecular Function
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0046872 metal ion binding
GO:0050178 phenylpyruvate tautomerase activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005615 extracellular space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3rf5, PDBe:3rf5, PDBj:3rf5
PDBsum3rf5
PubMed21944748
UniProtA4GRE3

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