Structure of PDB 3rf3 Chain B

Receptor sequence
>3rf3B (length=258) Species: 9606 (Homo sapiens) [Search protein sequence]
MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAA
VSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPY
SVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEV
VETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKE
LLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQL
TSWDEDAW
3D structure
PDB3rf3 Novel vinculin binding site of the IpaA invasin of Shigella.
ChainB
Resolution1.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R7 Q180 Q185 R188 R7 Q180 Q185 R188
BS02 peptide B T8 S11 I12 V16 Q19 I20 P43 V47 A50 N53 L54 V57 G58 E60 L108 T8 S11 I12 V16 Q19 I20 P43 V47 A50 N53 L54 V57 G58 E60 L108
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3rf3, PDBe:3rf3, PDBj:3rf3
PDBsum3rf3
PubMed21525010
UniProtP18206|VINC_HUMAN Vinculin (Gene Name=VCL)

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