Structure of PDB 3raw Chain B

Receptor sequence
>3rawB (length=349) Species: 9606 (Homo sapiens) [Search protein sequence]
VEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVAL
KIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIA
FELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLK
PENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIV
ATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVM
MEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYM
LQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHT
3D structure
PDB3raw Crystal Structure of human CDC-like kinase 3 isoform with a benzo-dioxol ligand
ChainB
Resolution2.09 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D283 K285 N288 D320 T337
Catalytic site (residue number reindexed from 1) D148 K150 N153 D185 T202
Enzyme Commision number 2.7.12.1: dual-specificity kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3RA B E164 F167 A184 K186 F236 L239 E287 L290 D320 E29 F32 A49 K51 F101 L104 E152 L155 D185
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3raw, PDBe:3raw, PDBj:3raw
PDBsum3raw
PubMed
UniProtP49761|CLK3_HUMAN Dual specificity protein kinase CLK3 (Gene Name=CLK3)

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