Structure of PDB 3r7n Chain B

Receptor sequence
>3r7nB (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
KMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVA
DMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
3D structure
PDB3r7n Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis.
ChainB
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.55: caspase-2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B A376 M377 R378 N379 T380 W385 G419 Y420 A22 M23 R24 N25 T26 W31 G65 Y66
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3r7n, PDBe:3r7n, PDBj:3r7n
PDBsum3r7n
PubMed21828056
UniProtP42575|CASP2_HUMAN Caspase-2 (Gene Name=CASP2)

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