Structure of PDB 3qzr Chain B

Receptor sequence
>3qzrB (length=176) Species: 39054 (Enterovirus A71) [Search protein sequence]
DFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLV
NVLDAVELVDEQGVNLALTLITLDTNEKFRDITKFIPENISTASDATLVI
NTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSV
GKIIGIHIGGNGRQGFCAGLKRSYFA
3D structure
PDB3qzr Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
ChainB
Resolution1.039 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H40 A71 G145 C147
Catalytic site (residue number reindexed from 1) H36 A67 G141 C143
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AG7 B H40 L125 N126 L127 S128 T142 A144 C147 H161 G163 G164 N165 F170 H36 L121 N122 L123 S124 T138 A140 C143 H157 G159 G160 N161 F166
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0018144 RNA-protein covalent cross-linking
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
Cellular Component
GO:0005737 cytoplasm
GO:0030430 host cell cytoplasm
GO:0039618 T=pseudo3 icosahedral viral capsid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3qzr, PDBe:3qzr, PDBj:3qzr
PDBsum3qzr
PubMed21813612
UniProtE7E815

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