Structure of PDB 3qnw Chain B

Receptor sequence
>3qnwB (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
LPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELL
TLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFFPKS
3D structure
PDB3qnw Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation.
ChainB
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.59: caspase-6.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E214 G215 Y216 Y217 S218 H219 W227 A269 K272 K273 E15 G16 Y17 Y18 S19 H20 W28 A70 K73 K74
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3qnw, PDBe:3qnw, PDBj:3qnw
PDBsum3qnw
PubMed21820899
UniProtP55212|CASP6_HUMAN Caspase-6 (Gene Name=CASP6)

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