Structure of PDB 3qjl Chain B

Receptor sequence

>3qjlB (length=240) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence]

HMRIEVKLLPLKDNPILPFNYNYEVYSQILEKVNSIEPTIAKLLSSPHGF
WTFSRIIVRKRKILPDKGIEILSDDVSLYISSSNEDIIRAIAEAVEKSPE
FKIGELSFLVGDIKAIKVKELGKENVFSTLSPIVVRTVKFEGNKLRHWDL
YPHDELFMDRLRKVMILRYSEVMGETPKDRDFTIEVLKFKPTRLMVGSSY
IRGSLMVFRYAGSEEIARFGYENGFGEKTGLGFGMVKLIE

3D structure

PDB

3qjl Cooperative and Specific Binding of a RAMP Protein to Single-stranded CRISPR Repeat RNA

Chain

Resolution

2.7009 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	B	F18 Y20 R54 R60 K61 I62 I68 E140 R145 W147 D148 K189 P190 T191 R192 Y199 R201	F19 Y21 R55 R61 K62 I63 I69 E141 R146 W148 D149 K190 P191 T192 R193 Y200 R202
BS02	rna	B	R2 V57 R58 R60 Y78 I115 K116 L186 K187 K236 I238 E239	R3 V58 R59 R61 Y79 I116 K117 L187 K188 K237 I239 E240

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0016788	hydrolase activity, acting on ester bonds

	Biological Process
GO:0051607	defense response to virus

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Molecular Function

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Biological Process

External links

PDB	RCSB:3qjl, PDBe:3qjl, PDBj:3qjl
PDBsum	3qjl
PubMed
UniProt	O58088\|CAS6L_PYRHO Putative CRISPR-associated endoribonuclease-like protein Cas6nc (Gene Name=cas6nc)

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