Structure of PDB 3qhr Chain B

Receptor sequence
>3qhrB (length=261) Species: 10090 (Mus musculus) [Search protein sequence]
SNEVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEV
GEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIY
PPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLH
LQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQS
WPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHSKYHSV
SLLNPPETLSV
3D structure
PDB3qhr Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis.
ChainB
Resolution2.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I270 Y271 I99 Y100
BS02 peptide B E224 Y225 K226 Q254 Y271 E277 I281 T285 E53 Y54 K55 Q83 Y100 E106 I110 T114
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:3qhr, PDBe:3qhr, PDBj:3qhr
PDBsum3qhr
PubMed21565702
UniProtP51943|CCNA2_MOUSE Cyclin-A2 (Gene Name=Ccna2)

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