Structure of PDB 3q95 Chain B

Receptor sequence
>3q95B (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
RSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNL
ADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHP
GKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLK
SIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQ
QHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
HAP
3D structure
PDB3q95 Crystal structure of human estrogen receptor alpha LBD in complex with GRIP peptide and Estriol
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 N359 K362 R363 L372 V376 E380 D538 L539 E542 I59 N60 K63 R64 L73 V77 E81 D239 L240 E243
BS02 ESL B E353 L387 F404 H524 L525 E54 L88 F105 H225 L226
External links
PDB RCSB:3q95, PDBe:3q95, PDBj:3q95
PDBsum3q95
PubMed
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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