Structure of PDB 3q5l Chain B

Receptor sequence
>3q5lB (length=214) Species: 5664 (Leishmania major) [Search protein sequence]
NLYFQGMTETFAFQAEINQLMSLIINTFYSNKEIFLRELISNASDACDKI
RYQSLTDPSVLGESPRLCIRVVPDKENKTLTVEDNGIGMTKADLVNNLGT
IARSGTKAFMEALEAGGDMSMIGQFGVGFYSAYLVADRVTVTSKNNSDES
YVWESSAGGTFTITSTPESDMKRGTRITLHLKEDQMEYLEPRRLKELIKK
HSEFIGYDIELMVE
3D structure
PDB3q5l Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin.
ChainB
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 KX2 B Q13 M104 Q19 M110
BS02 KX2 B N36 D39 A40 K43 D78 D87 N91 R97 G120 V121 G122 F123 N42 D45 A46 K49 D84 D93 N97 R103 G126 V127 G128 F129
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3q5l, PDBe:3q5l, PDBj:3q5l
PDBsum3q5l
PubMed
UniProtQ4Q4I6

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