Structure of PDB 3q36 Chain B

Receptor sequence
>3q36B (length=178) Species: 9606 (Homo sapiens) [Search protein sequence]
ISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTL
EQALQFWKQEFIKGKMDPDKFDKGYSYNIRHSFDYTPFSCLKIILSNPPS
QGDYHGCPFRHSDPELLKQKLQSYKISPGGISQILDLVKGTHYQVACQKY
FEMIHNVDDCGFSLNHPNQFFCESQRIL
3D structure
PDB3q36 Crystal structure of the C-terminal domain of human DNA primase large subunit: Implications for the mechanism of the primase - polymerase alpha switch.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 B P285 C287 C367 C384 F386 C424 P444 P15 C17 C90 C107 F109 C147 P167
Gene Ontology
Biological Process
GO:0006269 DNA replication, synthesis of primer

View graph for
Biological Process
External links
PDB RCSB:3q36, PDBe:3q36, PDBj:3q36
PDBsum3q36
PubMed21346410
UniProtP49643|PRI2_HUMAN DNA primase large subunit (Gene Name=PRIM2)

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