Structure of PDB 3q2v Chain B

Receptor sequence

>3q2vB (length=440) Species: 10090 (Mus musculus) [Search protein sequence]

DWVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVGV
FIIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTD
QNDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTI
VSQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEG
LSTTAKAVITVKDINDNAPVFNPSTYQGQVPENEVNARIATLKVTDDDAP
NTPAWKAVYTVVNDPDQQFVVVTDPTTNDGILKTAKGLDFEAKQQYILHV
RVENEEPFEGSLVPSTATVTVDVVDVNEAPIFMPAERRVEVPEDFGVGQE
ITSYTAREPDTFMDQKITYRIWRDTANWLEINPETGAIFTRAEMDREDAE
HVKNSTYVALIIATDDGSPIATGTGTLLLVLLDVDPDLPP

3D structure

PDB

3q2v The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.

Chain

Resolution

3.4 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	B	E11 D67 E69 D103	E11 D67 E69 D103
BS02	CA	B	E11 R68 E69 D100 Q101 D103 D136	E11 R68 E69 D100 Q101 D103 D136
BS03	CA	B	N102 N104 D134 D136 N143 D195	N102 N104 D134 D136 N143 D195
BS04	CA	B	E119 D180 E182 D216	E119 D180 E182 D216
BS05	CA	B	E119 E182 D213 I214 D216 D248	E119 E182 D213 I214 D216 D248
BS06	CA	B	N215 N217 D246 D248 A254 N304	N215 N217 D246 D248 A254 N304
BS07	CA	B	E232 E291 D325 V326 E328 D360	E232 E291 D325 V326 E328 D360
BS08	CA	B	E232 D289 F290 E291 E328	E232 D289 F290 E291 E328
BS09	CA	B	N327 E328 P330 E358 D360 Q365 D415	N327 E328 P330 E358 D360 Q365 D415
BS10	CA	B	E343 E397 D433 V434 D464	E343 E397 D433 V434 D437
BS11	CA	B	D462 D464	D435 D437
BS12	CA	B	E343 D395 E397	E343 D395 E397
BS13	MAN	B	S126 V171	S126 V171
BS14	MAN	B	K129 S131	K129 S131
BS15	MAN	B	R301 P314 T316	R301 P314 T316
BS16	MAN	B	H299 T316 A317 T318	H299 T316 A317 T318
BS17	MAN	B	I420 T422	I420 T422
BS18	MAN	B	T422 T424	T422 T424

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609	cell-cell adhesion

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:3q2v, PDBe:3q2v, PDBj:3q2v
PDBsum	3q2v
PubMed	21300292
UniProt	P09803\|CADH1_MOUSE Cadherin-1 (Gene Name=Cdh1)

[Back to BioLiP]