Structure of PDB 3q1f Chain B

Receptor sequence
>3q1fB (length=260) Species: 562 (Escherichia coli) [Search protein sequence]
AVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCGTSKVMAAA
AVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQ
YSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPR
DTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTS
WTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLA
SAARIIAEGL
3D structure
PDB3q1f CTX-M-9 S70G mutant in complex with hydrolyzed piperacillin
ChainB
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G70 K73 S130 E166 K234 S237
Catalytic site (residue number reindexed from 1) G42 K45 S102 E138 K206 S209
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YPP B G70 K73 N104 Y105 S130 P167 N170 G236 S237 G238 D239 G42 K45 N76 Y77 S102 P139 N142 G208 S209 G210 D211
BS02 YPP B T194 L195 R204 K212 T230 W250 P256 T166 L167 R176 K184 T202 W222 P228
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:3q1f, PDBe:3q1f, PDBj:3q1f
PDBsum3q1f
PubMed
UniProtQ9L5C8

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