Structure of PDB 3pzc Chain B

Receptor sequence
>3pzcB (length=276) Species: 375 (Bradyrhizobium japonicum) [Search protein sequence]
DPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRF
PPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTT
SLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLD
RLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYALKFE
LLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHTGCVAFGMDRL
AVAMFHTHGTDLSAWPAKVRDILGLQ
3D structure
PDB3pzc Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C131 R159 E161 R168 E176 K235 A250 S253 C279 R286
Catalytic site (residue number reindexed from 1) C114 R142 E144 R151 E159 K198 A213 S216 C242 R249
Enzyme Commision number 6.2.1.n2: amino acid--[acyl-carrier-protein] ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C131 E176 C279 C114 E159 C242
BS02 COA B R159 L169 F172 M174 K235 E237 S253 N255 R286 R142 L152 F155 M157 K198 E200 S216 N218 R249
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation

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Molecular Function
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Biological Process
External links
PDB RCSB:3pzc, PDBe:3pzc, PDBj:3pzc
PDBsum3pzc
PubMed
UniProtQ89VT8|AACL1_BRADU Amino acid--[acyl-carrier-protein] ligase 1 (Gene Name=bll0957)

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