Structure of PDB 3pqz Chain B

Receptor sequence
>3pqzB (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNQGFVLSLCH
LQKVKHYLILPSEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLR
HCCTR
3D structure
PDB3pqz Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression
ChainB
Resolution2.413 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R438 R458 Q461 R16 R36 Q39
BS02 peptide B R438 K478 H479 Y480 L481 L483 M495 D496 Q499 R16 K55 H56 Y57 L58 L60 M71 D72 Q75
External links
PDB RCSB:3pqz, PDBe:3pqz, PDBj:3pqz
PDBsum3pqz
PubMed21802427
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

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