Structure of PDB 3pao Chain B

Receptor sequence
>3paoB (length=314) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
YEWLNALPKAELHLHLEGTLEPELLFALAERNRIALPWNDVETLRKAYAF
NNLQEFLDLYYAGADVLRTEQDFYDLTWAYLQKCKAQNVVHVEPFFDPQT
HTDRGIPFEVVLAGIRAALRDGEKLLGIRHGLILSFLRHLSEEQAQKTLD
QALPFRDAFIAVGLDSSEVGHPPSKFQRVFDRARSEGFLTVAHAGEEGPP
EYIWEALDLLKVERIDHGVRAFEDERLMRRLIDEQIPLTVCPLSNTKLCV
FDDMSQHTILDMLERGVKVTVNSDDPAYFGGYVTENFHALQQSLGMTEEQ
ARRLAQNSLDARLV
3D structure
PDB3pao The crystal structure of adenosine deaminase with adenine bound from Pseudomonas aeruginosa
ChainB
Resolution2.493 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H16 H18 H196 E199 H220 D277
Catalytic site (residue number reindexed from 1) H13 H15 H193 E196 H217 D274
Enzyme Commision number 3.5.4.2: adenine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H16 H18 H196 D277 H13 H15 H193 D274
BS02 ADE B H18 L56 L60 Y63 S169 H196 E199 D277 D278 H15 L53 L57 Y60 S166 H193 E196 D274 D275
Gene Ontology
Molecular Function
GO:0000034 adenine deaminase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0019239 deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006146 adenine catabolic process
GO:0009117 nucleotide metabolic process
GO:0043103 hypoxanthine salvage

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3pao, PDBe:3pao, PDBj:3pao
PDBsum3pao
PubMed
UniProtQ9I6Y4|ADE_PSEAE Adenine deaminase (Gene Name=PA0148)

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