Structure of PDB 3p8h Chain B

Receptor sequence
>3p8hB (length=310) Species: 9606 (Homo sapiens) [Search protein sequence]
WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMY
FILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQP
PKGYFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNP
SLVCVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKP
LTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRPPHSFLVNMKLEAVD
RRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSK
TGHPLQPPLG
3D structure
PDB3p8h Small-molecule ligands of methyl-lysine binding proteins.
ChainB
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P8H B D355 N358 C363 F379 W382 Y386 D146 N149 C154 F170 W173 Y177 BindingDB: IC50=21000nM
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3p8h, PDBe:3p8h, PDBj:3p8h
PDBsum3p8h
PubMed21417280
UniProtQ9Y468|LMBL1_HUMAN Lethal(3)malignant brain tumor-like protein 1 (Gene Name=L3MBTL1)

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