Structure of PDB 3p37 Chain B

Receptor sequence
>3p37B (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLKYFRNYMSEHLLKAGANITPRELARLPYLRTWFRTRSAIILHL
SNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKE
LASRLRYARTMVDKLLSSR
3D structure
PDB3p37 From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
ChainB
Resolution2.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B W414 V415 D416 Y417 D419 Y481 F482 Y485 H489 L490 L491 H538 K540 W42 V43 D44 Y45 D47 Y109 F110 Y113 H117 L118 L119 H163 K165
External links
PDB RCSB:3p37, PDBe:3p37, PDBj:3p37
PDBsum3p37
PubMed21472932
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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