Structure of PDB 3oz1 Chain B

Receptor sequence
>3oz1B (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
FSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFC
CDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQ
LLST
3D structure
PDB3oz1 Recognition of Smac-mimetic compounds by the BIR3 domain of cIAP1
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C300 C303 H320 C327 C48 C51 H68 C75
BS02 BMB B D297 G306 L307 R308 C309 W310 E311 D314 W323 D45 G54 L55 R56 C57 W58 E59 D62 W71 BindingDB: IC50=<2nM
External links
PDB RCSB:3oz1, PDBe:3oz1, PDBj:3oz1
PDBsum3oz1
PubMed20954235
UniProtQ13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Gene Name=BIRC2)

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