Structure of PDB 3os0 Chain B

Receptor sequence
>3os0B (length=184) Species: 11963 (Human spumaretrovirus) [Search protein sequence]
DRPQKPFDKFFIDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTKAPSTSA
TVKSLNVLTSIAIPKVIHSDQGAAFTSSTFAEWAKERGIHLEFSTPYHPQ
SSGKVERKNSDIKRLLTKLLVGRPTKWYDLLPVVQLALNNTYSPVLKYTP
HQLLFGIDSNTPFANQDTLDLTREEELSLLQEIR
3D structure
PDB3os0 The mechanism of retroviral integration from X-ray structures of its key intermediates
ChainB
Resolution2.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D128 D185 D13 D70
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3os0, PDBe:3os0, PDBj:3os0
PDBsum3os0
PubMed21068843
UniProtP14350|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)

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